Melanotan 2 Half Life: How Often Should You Take MT2

Melanotan 2 is a synthetic peptide often used for skin tanning or enhancing libido. A crucial factor for effective application is the half-life of this active ingredient.

In this article, you'll learn everything you need to know about the half-life of Melanotan 2 and what this means for optimal application.

What Does Half-Life Mean?

Before we specifically address the half-life of Melanotan 2, we should clarify what this term actually means.

The half-life describes the time it takes for the concentration of a substance in the blood to decrease by 50%. For example, if the half-life of a particular substance is 2 hours, then after this time only 50% of the original amount remains in the body. After another 2 hours, only 25% remains, and so on. After approximately 5 to 7 half-lives, the substance is practically completely eliminated from the body.

For effective application, a substance should be taken at regular intervals based on its half-life. This ensures that the active ingredient concentration in the body remains at an optimal level.

The Half-Life of Melanotan 2

The half-life of Melanotan 2 was studied in mice back in 1994. The results of this study showed that MT2 has a half-life of about 1 to 2 hours in mice [R].

But can this result be directly applied to humans?

Probably not. Numerous user reports suggest that the half-life of MT2 in humans is significantly longer than just two hours. Some sources even mention a half-life of about 33 hours [R]. If this value is accurate, it would take approximately 165 to 231 hours (5 to 7 half-lives) for the peptide to be completely eliminated from the body.

This seems a bit too long to me, and I think the truth likely lies somewhere between these two extremes. Nevertheless, valuable insights can be derived from these findings to establish an appropriate dosing frequency for MT2.

When and How Often Should You Take Melanotan 2?

Based on the half-life that likely falls somewhere between 1 and 33 hours, taking MT2 once daily should be sufficient.

Since Melanotan 2 develops its effect in combination with UV radiation, it should be taken on days when sun exposure is planned.

Ideally, the peptide should be taken about 30 minutes before sun or UV exposure to achieve the best results.

You can learn more about this in our Melanotan 2 Dosage Guide.

Conclusion

The half-life of Melanotan 2 varies considerably depending on the source – animal studies show 1-2 hours, while some sources report a half-life of 33 hours in humans. Based on these findings, daily application of MT2 is sufficient to achieve effective results. For maximum effectiveness, the peptide should be taken 30 minutes before UV exposure, ensuring the active ingredient is working in the body at the right time.